Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance

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Peroxisome Proliferator-Activated Receptors and Hepatitis C Virus-Induced Insulin Resistance

Insulin resistance and type 2 diabetes are associated with hepatitis C virus infection. A wealth of clinical and experimental data suggests that the virus is directly interfering with the insulin signalling in hepatocytes. In the case of at least one viral genotype (the type 3a), insulin resistance seems to be directly mediated by the downregulation of the peroxisome proliferator-activated rece...

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ژورنال

عنوان ژورنال: PPAR Research

سال: 2009

ISSN: 1687-4757,1687-4765

DOI: 10.1155/2009/483485